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Vidalista 40 mg contains Tadalafil, a PDE5 inhibitor used to treat erectile dysfunction (ED) by improving blood flow to the penis. It’s a powerful medication with effects that can last up to 36 hours. It is not safe to use Vidalista 40 mg with other ED medications. Doing so can lead to serious side effects and health risks. Always use ED drugs exactly as prescribed by your doctor for safe and effective results. In rare cases where ED treatment fails with one medication, a doctor may recommend a change in drug or dosage — not combination therapy. The switch should be done under careful monitoring.