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Fildena 200mg is a powerful treatment for erectile dysfunction, but its high dose makes drug interactions more likely and more dangerous than with lower-dose options. That’s why it’s critical to consult with a healthcare provider before starting or combining it with other medications. Taking Fildena 200mg with certain drugs—particularly nitrates, alpha-blockers, HIV treatments, or antifungals—can result in serious or life-threatening complications. Even seemingly harmless substances like grapefruit juice or alcohol can significantly affect how Fildena 200mg works in the body.